BPS Pharmacotherapy (Part1 and Part2) - BPS-Pharmacotherapy Exam Practice Test
A 58-year-old man presents complaining of unsteady gait. Past medical history is significant for diabetes mellitus, gastroparesis, and depression. The patient exhibits a slight shuffling gait, mild limb rigidity, and decreased speed in performing rapid alternating movement. Current daily medications are bupropion, glyburide, metoclopramide, and omeprazole. Which of the following would be the most appropriate initial management for the presenting complaint?
Correct Answer: A
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Upon reviewing a clinical trial submission for publication, it is discovered that the authors have asked a medical Writer to help develop the manuscript after the data have been collected and analyzed by the authors. The medical Writer developed the manuscript, and the authors reviewed and edited the document before submitting it for publication. What is the most appropriate action for the authors to take?
Correct Answer: D
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A patient in an ICU has been receiving heparin 5,000 units subcutaneously three times daily for the last 7 days. Today the patient's platelet count has dropped by more than 50%, and the patient has developed a pulmonary embolism. The patient's heparin platelet factor 4 antibody test is positive.
What is the most appropriate treatment for this patient's pulmonary embolism?
What is the most appropriate treatment for this patient's pulmonary embolism?
Correct Answer: A
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A new team has been established in a large healthcare system to conduct research. At the first meeting of the new team, the pharmacotherapy specialist was asked to submit a proposal for a randomized clinical study. What is the first step in formulating the research hypothesis for this proposal?
Correct Answer: D
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A 60-year-old man who is HIV-positive describes symptoms of erectile dysfunction and requests therapy. Current medications include tenofovir 300 mg orally daily, emtricitabine 200 mg orally daily, atazanavir 300 mg orally daily, and ritonavir 100 mg orally daily. In addition to counseling on preventing HIV transmission, which recommendation is appropriate?
Correct Answer: D
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Healthcare Failure Mode and Effect Analysis (HFMEA) is described as a:
Correct Answer: C
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The Randomized Aldactone Evaluation Study (RALES) yielded the following results:
* Placebo death rate: 386/841
* Spironolactone death rate: 284/822
Given these data, which of the following is the relative risk reduction for death with spironolactone, in comparison with placebo?
* Placebo death rate: 386/841
* Spironolactone death rate: 284/822
Given these data, which of the following is the relative risk reduction for death with spironolactone, in comparison with placebo?
Correct Answer: D
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A 70-year-old 45-kg patient is admitted to the ICU with a diagnosis of digoxin intoxication. The patient complains of nausea, blurred vision, and fatigue that have been present for 3 days. A cardiac monitor reveals a HR of 42 bpm, an irregular rhythm, and a type second-degree heart block. Current medications include digoxin 0.25 mg and furosemide 40mg for heart failure, both taken daily at 0800. The patient remains adherent to all medications despite nausea, including today's doses. Blood is drawn at 1200 with the following results:
* Potassium: 6.0 mEq/L
* Creatinine: 2.3 mg/dL
* Digoxin: 1.7 ng/mL
Which of the following most appropriately describes the patient's digoxin concentration?
* Potassium: 6.0 mEq/L
* Creatinine: 2.3 mg/dL
* Digoxin: 1.7 ng/mL
Which of the following most appropriately describes the patient's digoxin concentration?
Correct Answer: B
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Using a new assay, the following readings for Drug X concentration in a blood sample are obtained: 45 ng/mL, 43 ng/mL, 45 ng/mL, 44 ng/mL, 45 ng/mL, and 45 ng/mL. The true concentration of the drug was reported as 65 ng/mL using the gold-standard assay.
On the basis of these data, the new assay should be characterized in which of the following categories?
On the basis of these data, the new assay should be characterized in which of the following categories?
Correct Answer: A
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A hospital's P & T Committee is considering whether a particular drug should be considered for therapeutic substitution. The pharmacotherapy specialist considers the acquisition cost of each medication and recommends using the drug with the lower cost. Which of the following types of analysis has the pharmacotherapy specialist used?
Correct Answer: C
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A 50-year-old patient presents to the physician complaining of anxiety, insomnia, a depressed mood, and decreased energy level. Paroxetine therapy is initiated. Which symptom will be the last to respond?
Correct Answer: D
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