Exam Name: Endocrinology and Diabetes (Specialty Certificate Examination)
Certification Provider: MRCPUK
Corresponding Certification: MRCPUK Certification
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Endocrinology and Diabetes (Specialty Certificate Examination): SEND Exam Premium File as PDF & Test Engine
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Last Updated: Sep 21, 2026
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Reading questions is one thing; sitting a timed exam is another. The Fast2test desktop and online test engines recreate the pace and pressure of the MRCPUK Endocrinology and Diabetes (Specialty Certificate Examination) testing environment, so SEND exam day feels like just another practice session.
MRCPUK SEND Exam Overview:
| Certification Vendor: | MRCP(UK) / Federation of the Royal Colleges of Physicians of the UK |
|---|---|
| Exam Name: | Endocrinology and Diabetes (Specialty Certificate Examination) |
| Exam Number: | SEND |
| Certificate Validity Period: | Valid indefinitely once awarded |
| Passing Score: | Variable scaled score (Angoff standard-setting, published post-exam) |
| Exam Format: | Computer-based, Images/Investigation data included, Clinical scenario-based, Single Best Answer (SBA/Best of Five) |
| Exam Duration: | 360 (180 minutes per paper, 1-hour break) |
| Available Languages: | English |
| Related Certifications: | CCT (Certificate of Completion of Training) MRCP(UK) CESR |
| Exam Price: | £585 (UK), £755 (International) - 2025/26 rates |
| Real Exam Qty: | 200 (100 per paper) |
| Recommended Training: | Society for Endocrinology Guidelines MRCP(UK) Official SCE Resources |
| Exam Registration: | My MRCP(UK) Online Application |
| Sample Questions: | MRCPUK SEND Sample Questions |
| Exam Way: | Computer-based at global Pearson VUE test centres; no online proctoring |
| Pre Condition: | No formal prerequisite; MRCP(UK) recommended; mandatory for CCT in Endocrinology & Diabetes |
| Official Syllabus URL: | https://www.mrcpuk.org/examinations/specialty-certificate-examinations/endocrinology-and-diabetes |
MRCPUK SEND Exam Syllabus Topics:
| Section | Weight | Objectives |
|---|---|---|
| Topic 1: Pituitary and Hypothalamic Disorders | 15% | - Hypopituitarism and hormone replacement - Diabetes insipidus and SIADH - Hypothalamic dysfunction - Pituitary adenomas: prolactinoma, acromegaly, Cushing's disease |
| Topic 2: Thyroid Disorders | 15% | - Thyroid nodules and cancer - Hyperthyroidism: Graves’ disease, toxic nodular disease - Thyroiditis and subclinical dysfunction - Hypothyroidism and myxoedema coma |
| Topic 3: Reproductive and Other Endocrine Conditions | 15% | - Polycystic ovary syndrome - Obesity and lipid disorders - Disorders of puberty and sex development - Endocrine hypertension and rare syndromes |
| Topic 4: Adrenal and Parathyroid/Metabolic Bone Disorders | 15% | - Hyperparathyroidism, hypoparathyroidism - Primary/secondary hyperaldosteronism - Cushing's syndrome, Addison's disease, phaeochromocytoma - Osteoporosis, osteomalacia, Paget's disease |
| Topic 5: Diabetes Mellitus | 40% | - Type 2 Diabetes
|
MRCPUK SEND FAQs: What Every Candidate Asks
The SEND exam, officially titled Endocrinology and Diabetes (Specialty Certificate Examination), is the qualifying test for the Specialty Certificate in Endocrinology and Diabetes certification from MRCP(UK) / Federation of the Royal Colleges of Physicians of the UK, a credential at the Specialist / Advanced level. Passing it proves you have the skills employers look for in certified professionals, and it can also support progress toward related credentials such as MRCP(UK), CCT (Certificate of Completion of Training), CESR.
The MRCPUK Endocrinology and Diabetes (Specialty Certificate Examination) exam gives you 360 (180 minutes per paper, 1-hour break) to work through 200 (100 per paper) questions. That is a steady pace with little room for second-guessing, so train yourself to read each question once, flag the difficult ones, and keep moving. Before exam day, sit at least two full timed sessions in the Fast2test test engine — when the clock feels familiar, it stops being a threat.
You need Variable scaled score (Angoff standard-setting, published post-exam) to pass, and the official registration fee is £585 (UK), £755 (International) - 2025/26 rates. Fall short and you pay that fee in full again for every retake, which makes solid preparation the cheaper option by far. Work through the Fast2test practice questions until you score comfortably above the passing mark, then book your seat.
No formal prerequisite; MRCP(UK) recommended; mandatory for CCT in Endocrinology & Diabetes Eligibility rules can change over time, so before you register, confirm the latest requirements on the official exam page: MRCP(UK) / Federation of the Royal Colleges of Physicians of the UK SEND exam overview.
You can book your SEND exam through any of these official registration channels:
The exam is delivered as Computer-based at global Pearson VUE test centres; no online proctoring, so you can pick the option that fits your schedule when you book.
MRCP(UK) / Federation of the Royal Colleges of Physicians of the UK recommends the following training for MRCPUK Endocrinology and Diabetes (Specialty Certificate Examination) candidates:
Pair that training with the 200 practice questions from Fast2test and you can check your readiness topic by topic before exam day.
Yes. Fast2test offers a free PDF demo for the MRCPUK Endocrinology and Diabetes (Specialty Certificate Examination) exam so you can judge the quality of our questions and answers before paying anything. Every purchase also comes with 365 days of free updates, and once that period expires you can extend your update service at a 50% discount.
Your purchase is protected by a 100% money-back guarantee. If you sit the corresponding SEND exam within 60 days of buying and do not pass, send us a scan of your exam enrollment slip together with your official Score Report (PDF) within 2 days of the exam date — the candidate name must match the payer's name — and we will process your full refund within 7 days. Please note that exams taken within 3 days of purchase, materials downloaded without ever sitting the exam, free products, and expired orders are not covered. If you would rather not have a refund, you can exchange your order for two exam products of equal value, free of charge, and keep the update service on your original purchase.
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The MRCPUK Endocrinology and Diabetes (Specialty Certificate Examination) syllabus is organized into 5 domains. The main areas include Pituitary and Hypothalamic Disorders (15%), Adrenal and Parathyroid/Metabolic Bone Disorders (15%), and Diabetes Mellitus (40%). Scroll up to the Exam Topics section above for the complete, current outline before you plan your study schedule.
MRCPUK Endocrinology and Diabetes (Specialty Certificate Examination) Sample Questions:
A 40-year-old man presented with a 4-month history of increasing central obesity. His medical history included HIV infection and allergic rhinitis. He was taking highly active antiretroviral therapy and nasal fluticasone.
On examination, he had marked central adiposity. His blood pressure was 160/95 mmHg.
Investigations:
serum sodium140 mmol/L (137-144)
serum potassium3.8 mmol/L (3.5-4.9)
serum cholesterol5.5 mmol/L (<5.2)
fasting serum triglycerides8.20 mmol/L (0.45-1.69)
serum cortisol (09.00 h)<50 nmol/L (200-700)
serum thyroid-stimulating hormone4.6 mU/L (0.4-5.0)
serum free T49.3 pmol/L (10.0-22.0)
What is the most likely diagnosis?
- A. Addison's disease
- B. glucocorticoid resistance
- C. hypothyroidism
- D. Cushing's syndrome
- E. HIV-associated lipodystrophy
Correct Answer: D 🗳️
A 42-year-old policewoman presented with thirst, polyuria and tiredness of 3 months' duration. She gave a family history of thyrotoxicosis.
On examination, her pulse was 108 beats per minute and her blood pressure was 150/70 mmHg. She had a fine tremor and diffuse thyroid enlargement. She also had mild proptosis.
Investigations:
haemoglobin146 g/L (115-165)
platelet count164 ? 109/L (150-400)
serum sodium143 mmol/L (137-144)
serum creatinine135 umol/L (60-110)
serum corrected calcium3.60 mmol/L (2.20-2.60)
serum thyroid-stimulating hormone<0.02 mU/L (0.4-5.0)
serum free T431.9 pmol/L (10.0-22.0)
serum free T315.6 pmol/L (3.0-7.0)
What is the most appropriate next investigation?
- A. 24-h urinary calcium
- B. fine-needle aspiration of thyroid
- C. plasma parathyroid hormone
- D. isotope bone scan
- E. serum phosphate
Correct Answer: C 🗳️
A 32-year-old woman presented to the outpatient clinic with a 1-year history of amenorrhoea that began after stopping her oral contraceptive pill. She had previously had two successful pregnancies and was otherwise well.
Examination was normal and no visual field defect was present on testing to confrontation.
Investigations:
serum sodium138 mmol/L (137-144) serum potassium3.8 mmol/L (3.5-4.9) plasma follicle-stimulating hormone2.0 U/L (2.5-10.0) plasma luteinising hormone2.0 U/L (2.5-10.0) serum prolactin1050 mU/L (<360)
MR scan of pituitarysee image
What is the most appropriate treatment?
- A. stereotactic pituitary radiosurgery
- B. octreotide
- C. cabergoline
- D. pituitary surgery
- E. bromocriptine
Correct Answer: D 🗳️
A 56-year-old man was referred to the diabetes clinic for conversion to insulin. He was taking metformin 1 g three times daily, gliclazide 160 mg twice daily and pioglitazone 45 mg daily. He drank no alcohol.
On examination, his body mass index was 41 kg/m2 (18-25). Abdominal examination showed a 2-cm, smooth, non-tender liver edge.
Which liver function test is the best marker of non-alcoholic fatty liver disease in type 2 diabetes mellitus?
- A. alanine aminotransferase
- B. aspartate aminotransferase
- C. bilirubin
- D. gamma glutamyl transferase
- E. alkaline phosphatase
Correct Answer: A 🗳️
A 54-year-old woman attended clinic for routine follow-up. She had Cushing's syndrome secondary to ectopic adrenocorticotropic hormone syndrome with no primary source identified.
She had declined bilateral adrenalectomy. Routine medication included metyrapone 500 mg three times daily, ketoconazole 200 mg once daily and hydrocortisone 10 mg in the morning and 5 mg in the evening.
Metyrapone inhibits the action of which enzyme in steroidogenesis?
- A. 5?-reductase
- B. 3?-hydroxysteroid dehydrogenase
- C. 17?-hydroxylase
- D. 21-hydroxylase
- E. 11?-hydroxylase
Correct Answer: E 🗳️
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