Updated Jan-2022 Pass FPGEE Exam - Real Practice Test Questions [Q26-Q46]

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Updated Jan-2022 Pass FPGEE Exam - Real Practice Test Questions

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NABP FPGEE Exam Syllabus Topics:

TopicDetails
Topic 1
  • Physicochemical properties relating to drug entities and dosage forms
  • Principles of bioavailability and bioequivalence
Topic 2
  • Function of the major body systems and homeostatic impact at organ and system level
  • Pharmacodynamics of drug binding and response
Topic 3
  • Interpret clinical pharmacokinetics of commonly used and low-therapeutic-index drugs
  • Materials and methods used in preparation of drug forms
Topic 4
  • Marketing of goods and services: product versus service pricing, distribution, promotion
  • Structure-activity relationships in relation to drug-target interactions
Topic 5
  • General microeconomic and general macroeconomic principles
  • Mechanisms of action of drugs of various categories including biologics
Topic 6
  • Role of automation and technology: pharmacy informatics, information management
  • Health care delivery financing in the United States
Topic 7
  • Utilize pharmacogenomics to calculate, evaluate, and individualize drug therapy
  • Classes of pharmacologically active natural products
Topic 8
  • Planning, including delineation between business and strategic planning
  • Concepts of crude drugs, semi-purified, and purified natural products
Topic 9
  • Social and Behavioral Aspects of Pharmacy Practice
  • Patient adherence to therapies and recommendations
Topic 10
  • Utilize pharmacokinetics to calculate, evaluate, and individualize drug therapy
  • Fundamental pharmacophores for drugs used to treat diseases

 

NEW QUESTION 26
Which of the following is not directly related to a drug toxicity of Nitroglycerin?

  • A. Tachycardia
  • B. Dizziness
  • C. Headaches
  • D. Projectile vomiting

Answer: D

 

NEW QUESTION 27
All are examples of drugs used in the treatment of bronchoconstriction, EXCEPT:

  • A. Xanthine oxidase inhibitors
  • B. 2-agonists
  • C. Leukotriene modifiers
  • D. Anticholinergic
  • E. Methyl xanthenes

Answer: D

 

NEW QUESTION 28
Bacterial resistance to an antibiotic may occurs due to:
I- Mutation
II- Adaptation
III- Gene transfer

  • A. III only
  • B. I only
  • C. I and II only
  • D. II and III only
  • E. All are correct

Answer: E

 

NEW QUESTION 29
If the total body clearance of a drug is 200 mL/min in a normal healthy adult and the renal clearance is 10
mL/min then one may assume that:

  • A. greater than normal drug accumulation would occur in patients with moderate renal failure.
  • B. the drug is not bound to plasma proteins.
  • C. the drug is concentrated in adipose tissue.
  • D. entero-hepatic recycling is significant.
  • E. the drug is extensively metabolized.

Answer: E

 

NEW QUESTION 30
Mechanism of action of enalapril is:

  • A. Inhibits bone resorption
  • B. Inhibits angiotensin converting enzyme
  • C. serotonin reuptake inhibitor
  • D. beta-2 agonist
  • E. Induces "freezing" of initiation complex

Answer: B

 

NEW QUESTION 31
Mechanism of action of vancomycin is:

  • A. Inhibits transpeptidase
  • B. Potentiates glucose-mediated insulin secretion
  • C. Inhibits bacterial cell wall synthesis
  • D. Mitotic spindle poison
  • E. Inhibits phospholipase C

Answer: C

 

NEW QUESTION 32
Otitis media is an ear infection normally caused by S.pneumoniae and may be best treated by:

  • A. Ampicillin
  • B. Penicillin V
  • C. Amoxicillin
  • D. Oxacillin
  • E. Amoxicillin clavulanate

Answer: E

 

NEW QUESTION 33
Resistance is the major problem with penicillins due to ability of bacteria to breakdown the lactam ring of
penicillin and inactivates the drug. To overcome these problem penicillins can be administrated together
with -lactamase inhibitors.
Examples of -lactamase inhibitors is/are:
I- Clavulanic acid
II- Sulbactam
III- Tazobactam

  • A. III only
  • B. I only
  • C. I and II only
  • D. II and III only
  • E. All are correct

Answer: E

 

NEW QUESTION 34
Mechanism of action of cocaine is:

  • A. Blocks catecholamine uptake by axonal terminal
  • B. Inhibits Na-Cl transporter
  • C. beta-2 agonist
  • D. Muscarinic agonist
  • E. beta-1 antagonist

Answer: A

 

NEW QUESTION 35
Pernicious anemia is:

  • A. treated by parenteral administration of folic acid.
  • B. treated by parenteral administration of vitamin B12.
  • C. prevented by oral administration of a vitamin B12 supplement.
  • D. due to dietary deficiency of vitamin B12.
  • E. caused by dietary iron deficiency.

Answer: B

 

NEW QUESTION 36
Which of the following are similarities between Cytochrome P450 and MAO?

  • A. All of the above
  • B. Both carry out oxidative deaminations
  • C. Both carry out direct heteroatom oxidations
  • D. Both add oxygen from O2 to substrates and also form water
  • E. Both carry out N-dealkylations

Answer: B

 

NEW QUESTION 37
Condition characterized by a reversible form of airflow obstruction is known as:

  • A. Cirrhose
  • B. Embolism
  • C. Jaundice
  • D. Aneurism
  • E. Emphesema

Answer: E

 

NEW QUESTION 38
True statements regarding the use of monoclonal antibodies include which of the following?
I Flu-like symptoms commonly occur at the start of therapy.
II T cells are blocked from initiating the rejection process.
III Orthoclone is a human immunoglobulin product.

  • A. I, II and III
  • B. III only
  • C. I only
  • D. I and II only
  • E. II and III only

Answer: D

 

NEW QUESTION 39
MT, a pharmacy technician, has worked in a community pharmacy for 5 years. He is well-trained and
welcomes new learning opportunities. His manager, now wanting to delegate a new technical project to
him, should:
I discuss suggested steps to accomplish the project.
II negotiate a time schedule for completion of the project.
III provide support and follow-up as required.

  • A. III only
  • B. I, II and III
  • C. I only
  • D. I and II only
  • E. II and III only

Answer: B

 

NEW QUESTION 40
Indication of aspirin is:

  • A. Cardiac arrest
  • B. Cyanide poisoning
  • C. Inflammation
  • D. Insomnia
  • E. Subarachnoid hemorrhage

Answer: C

 

NEW QUESTION 41
If the pKa of phenobarbital is 7.4, what approximate fraction of the drug would be ionized at pH 8.4?

  • A. 90%
  • B. 30%
  • C. 100%
  • D. 10%
  • E. 50%

Answer: A

 

NEW QUESTION 42
An enzyme is:

  • A. unable to hydrolyse polysaccharides
  • B. a catalyst
  • C. a nucleic acid
  • D. changed chemically in a reaction
  • E. an oligopeptide

Answer: B

 

NEW QUESTION 43
Potassium sparing diuretics have the primary effect upon the _____ found in the kidney.

  • A. Proximal convoluted tubule
  • B. Collecting duct
  • C. Distal convoluted tubule
  • D. Loop of Henle

Answer: C

 

NEW QUESTION 44
Heparin synthesized in the body and can be classified as:

  • A. Amino acid
  • B. Oligosaccharide
  • C. Disaccharide
  • D. Polysaccharide
  • E. Monosaccharideo

Answer: B

 

NEW QUESTION 45
Class of tocainide is:

  • A. Beta blockers
  • B. Cephalosporins
  • C. Antiarrhythmic agents
  • D. Thiazides
  • E. Autonomic nervous system drugs

Answer: C

 

NEW QUESTION 46
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